Physician Executive | Healthcare Innovator | Clinical Informatics | Artificial Intelligence | Public Health Leadership

Dr. Edward Kalpas is a dynamic and results-oriented physician executive with a passion for healthcare innovation and a demonstrated commitment to patient-centered care. His expertise spans clinical informatics, health technology, public health leadership, quality improvement, and lifestyle medicine.

Professional Background

With over 20 years of experience spanning clinical practice, health informatics, and public health leadership, Dr. Kalpas has established himself as a trusted voice in healthcare transformation. His career has been defined by leveraging data analytics and innovative technologies to improve patient outcomes, enhance healthcare quality, and address systemic disparities in care delivery.

Dr. Kalpas currently serves as Chief Medical Officer at Yavapai County Community Health Services and Community Health Center of Yavapai in Prescott, Arizona, where he provides strategic leadership and clinical oversight for public health programs and a Federally Qualified Health Center dedicated to providing accessible, high-quality healthcare to the Yavapai County community.

Previously, he held leadership positions as Associate Chief Medical Information Officer at HonorHealth, where he spearheaded clinical informatics initiatives and quality improvement projects. His diverse background includes roles as Associate Program Director for a Clinical Informatics Fellowship, Senior Medical Director at HVH Precision Analytics, Medical Officer at the New York State Quality Improvement Organization, and service as a Captain in the U.S. Army Medical Corps.

Areas of Expertise

Clinical Informatics & Health Technology

Dr. Kalpas specializes in designing and implementing clinical information systems that enhance decision-making, streamline workflows, and improve patient care. His expertise in Epic systems as a Physician Builder and his leadership in multiple informatics initiatives demonstrate his commitment to creating technology solutions that serve healthcare providers without adding to their administrative burden.

Artificial Intelligence in Healthcare

With specialized experience in leveraging data analytics and machine learning, Dr. Kalpas has contributed to the strategic application of AI to healthcare challenges. His work has included developing and implementing data-driven initiatives to improve healthcare quality, efficiency, and cost-effectiveness.

Public Health Leadership

Drawing on his background in population health and preventive medicine, Dr. Kalpas develops strategies to address community health challenges through data-driven approaches. His current role as Chief Medical Officer puts him at the forefront of public health initiatives, where he applies his expertise to improve community wellness and healthcare access.

Quality Improvement & Patient Safety

Dr. Kalpas has pioneered innovative approaches to quality improvement, including the development of a novel clinical decision support tool using NEWS2 for COVID-19 decompensation. His committee work on Institutional Review Boards and Research, Quality Improvement, and Patient Safety demonstrates his commitment to enhancing clinical outcomes across healthcare systems.

Medical Education & Research

As an educator and researcher, Dr. Kalpas is committed to preparing the next generation of healthcare professionals to thrive in an increasingly digital healthcare environment. His academic appointments at Arizona State University, TGen, and Stony Brook Medicine highlight his dedication to education. His research focuses on innovative healthcare delivery models like Project ECHO, precision medicine, and analyzing high-need populations, with findings published in journals such as the Journal of Primary Care & Community Health and Health Informatics Journal.

Lifestyle Medicine & Value-Based Care

Dr. Kalpas is board certified in Lifestyle Medicine, reflecting his commitment to preventive approaches to healthcare that empower patients to take an active role in their wellbeing through lifestyle modifications and proactive health management. He is a strong advocate for value-based care models that prioritize patient outcomes over volume.

Education & Credentials

M.D., Uniformed Services University, Bethesda, MD, 2002
M.P.H., Columbia University, New York, NY, 2007
M.A.S., Health Informatics, Arizona State University, Tempe, AZ, 2021
Advanced Certificate, Clinical Informatics, Stony Brook University, NY, 2018
B.S., Biophysical Chemistry, Dartmouth College, Hanover, NH, 1998
Clinical Informatics Fellowship, HonorHealth, Scottsdale, AZ, 2020-2021
Preventive Medicine Residency, Stony Brook Medicine, NY, 2015-2017
General Surgery Residency, Tripler Army Medical Center, Honolulu, HI, 2002-2004

Board Certifications

Board Certification in Public Health and General Preventive Medicine, ABPM
Board Certification in Clinical Informatics, ABPM
Board Certification in Lifestyle Medicine, ABLM

Professional Skills

Clinical Informatics
Health IT Leadership
Quality Improvement
Patient Safety
Data Analytics
Machine Learning
Medical Education
Public Health
Preventive Medicine
Health Economics
Medical Operations

Research & Publications

Dr. Kalpas’s research spans multiple areas including identifying high-cost, high-need patients, physician perceptions of sensitive medical records, artificial intelligence in healthcare, and innovative curriculum development in imaging informatics. His work has been published in journals such as the Journal of Primary Care & Community Health, Health Informatics Journal, Cureus, and Journal of Digital Imaging.

He has led important research initiatives including Project ECHO programs for Palliative Care and Medications for Opioid Use Disorder, as well as collaborating on innovative studies with the Translational Genomics Research Institute and the National Covid Cohort Collaborative.

Dr. Kalpas is also a published author, contributing to “USMLE Step 2 CS Strategies, Practice & Review” by Kaplan Medical.

Special Interests

Patient Empowerment
Data-Driven Healthcare
Health Equity
Healthcare Innovation

Vision & Philosophy

Dr. Kalpas envisions a healthcare system where technology serves as a bridge rather than a barrier—connecting patients with providers, enhancing clinical decision-making, and making quality care accessible to all. He believes that meaningful healthcare transformation requires a multidisciplinary approach that values the perspectives of clinicians, patients, technologists, and public health experts.

His work is guided by a commitment to:

Patient-centered care that respects individual needs and preferences
Evidence-based approaches that leverage data to improve outcomes
Equity in healthcare access and delivery
Technological innovation that enhances rather than replaces human connection
Preventive strategies that address health challenges before they become acute

Connect With Dr. Kalpas

Dr. Kalpas welcomes opportunities for collaboration, speaking engagements, and media inquiries related to clinical informatics, healthcare technology, and public health leadership.